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Volumetric MRI produces Alzheimer's early warning

(PSYCHIATRIC TIMES) - MRI measures of regional brain atrophy, taken at the University of California, San Diego, have established the basis for a new way to diagnose Alzheimer's disease.

Radiology professors Andres Dale, Ph.D., and Dr. Carl Hoh, neurologist Dr. James Brewer, and radiology resident Dr. David Karow saw that volumetric MRI potentially fulfilled the need for a less expensive and less invasive test for early diagnosis of the disease and for drug research and development.

Their suspicions were confirmed in a study involving MR and FDG-PET scans performed on 80 normal subjects, 69 subjects with single-domain mild cognitive impairment limited to memory loss, 156 subjects with MCI, and 68 mild Alzheimer's disease patients.

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