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o Explain to interested patients that older depressed patients who benefit from taking SSRIs should be screened regularly for osteoporosis and for possible preventive drug therapy.

MINNEAPOLIS, June 27 -- Selective serotonin reuptake inhibitors (SSRIs) have been linked to decreased bone density in older women and men, two related studies found.

The paired studies at different institutions, reported in the June 25 issue of the Archives of Internal Medicine, found an increase in the rate of bone loss in older women and separately in older men using SSRIs, but not in patients using tricyclic antidepressants.

However, in neither study were data available on dose or duration of use, the researches reported.

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