(PSYCHIATRIC TIMES) - WACOL, Australia, Oct. 5 -- Schizophrenia leads to an age-related mortality rate that is about 2.5 times that of the general population, and the difference appears to be increasing, researchers here reported.
Suicide, which was more than 12 times more likely among people with schizophrenia, was the leading cause-specific mortality risk, John McGrath, M.D., Ph.D., of the Park Center for Mental Health, and colleagues, reported in the October issue of Archives of General Psychiatry.
The investigators examined the standardized mortality ratios (SMRs), which were calculated by dividing the observed mortality reported in 37 schizophrenia studies by the expected mortality rates as predicted by age and sex in the general population. The studies, conducted in 25 countries, were published from Jan. 1, 1980 through Jan. 31, 2006.
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