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Meta-Analysis Finds Antidepressants' Benefits Counter Risks for Kids

(PSYCHIATRIC TIMES) - MedPage Today Action Points

o Explain to patients who ask that this large study found that pediatric antidepressants were most effective for certain anxiety disorders followed by major depression.

o Inform interested patients, that the 1% increased risk of suicidal thoughts or attempts in these young people was not statistically significant and that there were no actual suicides.

COLUMBUS, OH, April 17 -- The benefits of antidepressants for children and teenagers with depression or anxiety disorders may outweigh their risks, according to a large meta-analysis.

What's more, the small increased suicidal risks that have been reported were not statistically significant, found the results of analysis, which were reported in the April 18 issue of the Journal of the American Medical Association.

The analysis of pediatric antidepressant treatment of major depressive disorder, obsessive-compulsive disorder, and other anxiety disorders showed efficacy for all three conditions, wrote Jeffrey A. Bridge, Ph.D., of Ohio State University in Columbus, and David A. Brent, M.D., of the University of Pittsburgh, and colleagues.

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