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Folate Weakly Linked to Reduced Alzheimer's Disease Risk

(PSYCHIATRIC TIMES) - MedPage Today Action Points

o Explain to patients who ask that this observational study does not by itself support increasing folate intake to prevent Alzheimer's.

o Inform interested patients that this study was conducted in a primarily African American and Hispanic female population.

NEW YORK, Jan. 8 -- Folate appears associated with a lower risk of Alzheimer's disease, although the relationship is tenuous, according to an observational study here.

In the study of older, predominantly African-American and Hispanic women, a 50% reduction in the risk of Alzheimer's was found only for those consuming the highest amount of folate (488 µg or more), and only after adjusting for vitamin B intake, said José A. Luchsinger, M.D., of Columbia University, and colleagues.

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