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Early Intervention in a Case of Migraine With Depression

(PSYCHIATRIC TIMES) - THE CASE: The patient—a 25-year-old white woman employed as a fourth-grade teacher—presented with left-sided, throbbing headaches that had gradually increased in severity and frequency.

Her headaches began at age 13 with menarche. These headaches, which occurred once or twice a month, were associated with photophobia, phonophobia, and nausea, and usually lasted 8 to 12 hours. They gradually progressed in severity (from mild/moderate to moderate/severe) and frequency (to 2 or 3 per week). The headaches affected the patient's job performance and attendance, and she complained of fatigue, lack of sleep, and difficulty in concentrating. She also reported increasing stress in her home life: after her husband lost his job a year earlier, she had been the sole support of her family, including her 2 young children.

The patient had been taking aspirin/butalbital/caffeine tablets for her headaches. She increased the dosage to obtain pain relief, but nausea and/or heartburn developed as a result. She occasionally resorted to the emergency department, where she received meperidine. She had previously treated her headaches with acetaminophen/aspirin/ caffeine tablets and, before that, with ibuprofen and acetaminophen.

This patient was 5 ft 5 ½ in tall and weighed 125 lb. Results of the neurologic examination were normal. Her heart rate was 78 beats per minute and regular, and her blood pressure was 110/74 mm Hg. Her chest was clear, and she appeared well nourished and otherwise healthy. However, she exhibited signs of depression.

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