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o Explain to interested patients that this study suggests that inflammatory responses to stress are elevated in those who are depressed, a finding that could explain in part why depression is associated with diseases known to have an inflammatory component, such as heart disease, cancer and diabetes.

ATLANTA, Sept. 1 -- Men with major depression have an exaggerated inflammatory response to stress, a finding that could partly explain some of the somatic diseases associated with the condition, according to researchers here.

They believe that the finding may shed some light on why conditions such as heart disease, cancer, and diabetes often go hand in hand with depression.

This small study is the first to demonstrate such an exaggerated response in major depression patients compared with controls, reported Andrew H. Miller, M.D., of Emory University School of Medicine, and colleagues, in the Sept. 1 issue of the American Journal of Psychiatry.

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