Connecting Psychiatry - Expert community for all mental health professionals

Celexa Effective Against Depression with Heart Patients

(PSYCHIATRIC TIMES) - MedPage Today Action Points

o Explain to interested patients that when depression accompanies coronary artery disease, two SSRI antidepressants, Celexa and Zoloft, now show evidence of efficacy,

o Point out that a large randomized clinical trial is still necessary to determine whether treatment of depression in these patients has beneficial effects on the occurrence of cardiovascular events.

MONTREAL, Jan 23 -- The selective serotonin reuptake inhibitor (SSRI) Celexa (citalopram) appears effective in treating depression among patients with coronary artery disease, researchers here found.

Celexa yielded a 31% greater response rate than placebo, but the addition of interpersonal psychotherapy did not increase the benefit, said François Lespérance, M.D., of the University of Montréal, and colleagues, in the Jan. 24-31 issue of the Journal of the American Medical Association.

The study adds to the scanty evidence for SSRI use in patients with coronary artery disease and depression, according to an accompanying editorial by Alexander H. Glassman, M.D., and J. Thomas Bigger Jr., M.D., both of Columbia in New York.

For full article, please visit:

Views: 3


You need to be a member of psychiatryRounds to add comments!

Join psychiatryRounds

psychiatryRounds Social Media


CMEinfo: Board Reviews in Anesthesia, Cardiology, Internal Medicine, Radiology

© 2020   Created by PsychiatryRounds Team.   Powered by

Badges  |  Report an Issue  |  Terms of Service