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(PSYCHIATRIC TIMES) - MedPage Today Action Points

o Explain to interested patients that the accumulation of beta amyloid in the brain is thought to be a key factor in the development of Alzheimer's Disease.

o Note that several animal studies have shown that a vaccine against beta amyloid can reduce the accumulation, but a human study had to be halted because of dangerous side effects.

o Explain that this study suggests that a transcutaneous vaccine might overcome the side effects, but caution that more research is needed before human trials can begin.

TAMPA, Fla., Jan. 23 -- A safe and effective vaccine against Alzheimer's disease may be back on track, this time by transdermal patch delivery, according to researchers here.

In experimental mice, transcutaneous vaccine administration with beta amyloid peptide sharply reduced the levels of beta amyloid proteins that muddy the brain in Alzheimer's, found Jun Tan, Ph.D., M.D., of the University of South Florida.

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