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(PSYCHIATRIC TIMES) - TAMPA, Fla., Jan. 23 -- A safe and effective vaccine against Alzheimer's disease may be back on track, this time by transdermal patch delivery, according to researchers here.

In experimental mice, transcutaneous vaccine administration with beta amyloid peptide sharply reduced the levels of beta amyloid proteins that muddy the brain in Alzheimer's, found Jun Tan, Ph.D., M.D., of the University of South Florida.

There was saw no sign of the worrisome side effects, including cerebral micro-hemorrhage and meningitis caused by T-cell infiltration, that had sidelined a human clinical trial of a similar vaccine delivered intraperitoneally, the researchers reported online in the Proceedings of the National Academy of Sciences.

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