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(PSYCHIATRIC TIMES) - MedPage Today Action Points

o Explain to patients who ask that an international team of researchers has identified a gene that may play a role in the pathogenesis of late-onset Alzheimer's disease, the most common form of the disorder.

o Explain that this finding needs to be confirmed, but could form the basis for diagnostic or therapeutic approaches to Alzheimer's disease in the future.

TORONTO, Jan. 15 -- A second gene as a possible accessory in the development of late-onset Alzheimer's disease has been identified by an international team of researchers.

Inherited variants of the gene, called SORL1, short for sortilin-related receptor 1, may be indirectly involved in the abnormal production and deposition in the brain of beta-amyloid plaques, reported the researchers online in Nature Genetics.

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