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PsychiatryRounds Psychiatry News's Blog – September 2006 Archive (19)

Water in the Brain Hints at Early Cognitive Decline

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to interested patients that in this small study, researchers found evidence of subtle changes in the brains of patients with mild cognitive impairment that could be early signs of Alzheimer's disease.



IRVINE, Calif., Sept. 26 -- Early signs of Alzheimer's disease may show up in subtle changes in the diffusion of water in key brain structures, as revealed by MRI, researchers here suggested.



In a small… Continue

Added by psychiatryRounds Psychiatry News on September 26, 2006 at 11:30pm — No Comments

Acne Drug Makes Mice Depressed

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o When prescribing Accutane, caution patients that it has been linked in inconclusive case reports to a range of depressive symptoms.



o Advise that this study suggests that the active ingredient in the medication can cause depressive effects, at least in mice.



AUSTIN, Tex., Sept. 22 -- The widely used acne drug Accutane (isotretinoin) appears to cause depression in mice, according to researchers here and in… Continue

Added by psychiatryRounds Psychiatry News on September 22, 2006 at 11:30pm — No Comments

Accelerated Weight Loss May Signal Imminent Dementia Onset

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to interested patients that weight loss is a common feature of advanced age, and that the findings of this study - an association between accelerated weight loss and the risk of dementia -- need to be confirmed in larger studies.



ST. LOUIS, Sept. 11 -- An early warning sign for Alzheimer's disease could be accelerated weight loss, researchers here suggested.



Among more than 400 healthy older adults ages… Continue

Added by psychiatryRounds Psychiatry News on September 11, 2006 at 11:30pm — No Comments

Accelerated Weight Loss May Signal Imminent Dementia Onset

(PSYCHIATRIC TIMES) - ST. LOUIS, Sept. 11 -- An early warning sign for Alzheimer's disease could be accelerated weight loss, researchers here suggested.



Among more than 400 healthy older adults ages 65 to 95, followed as part of a longitudinal study of Alzheimer's, those who had a sudden doubling of the rate of weight loss developed dementia about a year later, found David K. Johnson, Ph.D., of Washington University, and colleagues.



"Specific factors contributing to weight… Continue

Added by psychiatryRounds Psychiatry News on September 11, 2006 at 11:30pm — No Comments

IBS Hints at Migraine, Fibromyalgia, and Depression

(PSYCHIATRIC TIMES) - BOSTON, Sept. 28 -- When a diagnosis of irritable bowel syndrome (IBS) comes to mind, consider migraine, fibromyalgia, and depression as well.



Patients with IBS were 60% more likely to have one of those conditions than were those who didn't have IBS, according to J. Alexander Cole, D.Sc., M.P.H., of Boston University, and colleagues, who studied nearly 100,000 IBS patients enrolled in a national health insurance plan.



Patients who were treated for IBS… Continue

Added by psychiatryRounds Psychiatry News on September 8, 2006 at 11:30pm — No Comments

Pregnant Drinking Increases Child's Risk of Alcohol Disorder

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Inform interested patients that alcohol intake during pregnancy, especially in the first six months, increases the risk that their child will later develop an alcohol disorder such as alcohol dependency.



o Caution patients of child-bearing age that many authorities believe no amount of alcohol consumption is safe during pregnancy.



HERSTON, Australia, Sept. 4 -- Children of mothers who drink during pregnancy… Continue

Added by psychiatryRounds Psychiatry News on September 4, 2006 at 4:00am — No Comments

Depression Ramps Up Inflammatory Response to Stress

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to interested patients that this study suggests that inflammatory responses to stress are elevated in those who are depressed, a finding that could explain in part why depression is associated with diseases known to have an inflammatory component, such as heart disease, cancer and diabetes.



ATLANTA, Sept. 1 -- Men with major depression have an exaggerated inflammatory response to stress, a finding that could… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 11:30pm — No Comments

Bipolar Disorders Depress Productivity

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to interested patients that depressive episodes that commonly occur with bipolar disorders may be severe and more persistent than those experienced by patients with major depressive disorder.



BOSTON, Sept. 1 -- Bipolar disorders cause twice as much lost time in the workplace as does major depression, according to a national mental health survey.



Workers with bipolar disorders who were surveyed reported… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 11:30pm — No Comments

Apathy and Depression in Parkinson Disease

(PSYCHIATRIC TIMES) - Is apathy in patients with Parkinson disease (PD) merely a symptom of depression or a core symptom of PD itself? In the July issue of Neurology, researchers from the University of Florida surveyed patients with PD, a population known to exhibit high rates of both depression and apathy, and patients who had dystonia, another subcortical disorder. Kirsch-Darrow and colleagues administered several mood questionnaires to 80 patients with PD and 20 patients with adult-onset… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 11:30pm — No Comments

Depression Rates High in Young Women With Acute MI

(PSYCHIATRIC TIMES) - Depression accompanying acute myocardial infarction (MI) is not uncommon. Likewise, depression among young women in the community is more prevalent than in men or women of any other age group. In a study published in the April issue of Archives of Internal Medicine, Dr Susmita Malik and colleagues sought to determine whether young women who were hospitalized with acute MI also had higher rates of depression than other groups.



The researchers interviewed 814… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 11:30pm — No Comments

PET tracer exploits new way to characterize dementia

(PSYCHIATRIC TIMES) - An early human trial with a new PET radiotracer has found that Alzheimer's disease and vascular dementia both lead to substantial losses of nicotinic acetylcholine receptors in the cerebral cortex. The study from Germany suggests similarities in the pathogenesis of the two diseases relating to the cholinergic system.



Dr. Osama Sabri, chair of nuclear medicine, and colleagues at the University of Leipzig discovered an overlapping relationship using fluorine-18… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 11:30pm — No Comments

Depression Ramps Up Inflammatory Response to Stress

(PSYCHIATRIC TIMES) - ATLANTA, Sept. 1 -- Men with major depression have an exaggerated inflammatory response to stress, a finding that could partly explain some of the somatic diseases associated with the condition, according to researchers here.



They believe that the finding may shed some light on why conditions such as heart disease, cancer, and diabetes often go hand in hand with depression.



This small study is the first to demonstrate such an exaggerated response in… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 11:30pm — No Comments

Cognitive Rx Reduces Depression in Breast Ca Pts

(PSYCHIATRIC TIMES) - AMELIA ISLAND, Florida—Individualized cognitive therapy (CT) is effective in reducing depression in women with metastatic breast cancer, Jose Savard, PhD, said at the American Psychosocial Oncology Society (APOS) Third Annual Conference (abstract II-2). Women with stage IV disease treated with CT had significantly lower depression scores after treatment, compared to untreated controls who remained on a waiting list to receive CT, reported Dr. Savard, associate professor of… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 11:30pm — No Comments

Psychotherapy for Social Anxiety Disorder

(PSYCHIATRIC TIMES) - Case vignette



After arriving early for his interview, David impressed the therapist as being calm and competent. He answered questions clearly and articulately. His voice did not quaver or shake, and he kept his hands neatly in his pockets. David made only occasional eye contact, but this made him seem distracted and aloof, rather than fearful. He was seeking treatment for social anxiety now, he explained, because he was on the verge of losing his job. An… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 10:00pm — No Comments

Bipolar Disorders Depress Productivity

(PSYCHIATRIC TIMES) - BOSTON, Sept. 1 -- Bipolar disorders cause twice as much lost time in the workplace as does major depression, according to a national mental health survey.



Workers with bipolar disorders who were surveyed reported losing an average of 65.5 lost work days a year, primarily during the depressive phase of the disease, reported Ronald C. Kessler, Ph.D., of Harvard Medical School, and colleagues in the Sept. 1 issue of the American Journal of Psychiatry. In contrast,… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 4:30am — No Comments

A Case of Pseudosomatization Disorder

(PSYCHIATRIC TIMES) - I read with interest Dr McCarron's article (Psychiatric Times, May 2006, page 32), "Somatization in the Primary Care Setting"--an important topic indeed.



He described irritable bowel, chronic fatigue, and fibromyalgia syndromes as systems developed by medical specialists to describe unexplained somatic symptoms. However, chronic fatigue and fibromyalgia are codified diseases with specific criteria.1,2



Dr McCarron described patients with somatization… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 4:30am — No Comments

The Role of Family Therapy for Adolescents With Anorexia Nervosa

(PSYCHIATRIC TIMES) - Anorexia nervosa (AN) is a serious psychiatric condition with a prevalence estimated at 0.48% to 0.7% among adolescent females aged 15 to 19 years.1 Comorbid psychological conditions are also common in patients with AN. Some 60% of patients with eating disorders have a lifetime anxiety or affective disorder. The mortality rates associated with this severely disabling condition are higher than for any other psychiatric disorder,2 with about half of the deaths occurring from… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 4:00am — No Comments

Catatonia in Autism or the Blind Men and the Elephant

(PSYCHIATRIC TIMES) - The sixth [blind man] no sooner had begun About the beast to grope, Then, seizing on the swinging tail That fell within his scope, 'I see,' quoth he, 'the Elephant Is very like a rope!' " -- From The Blind Men and the Elephantby John Godfrey Saxe (1816-1887)



Autistic spectrum disorders (ASD), as defined here, include autistic disorder, Asperger disorder, childhood disintegrative disorder (CDD), and pervasive developmental disorder not otherwise specified. They… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 3:30am — No Comments

ADHD in Girls: Wide Range of Negative Sequelae

(PSYCHIATRIC TIMES) - Attention-deficit/hyperactivity disorder (ADHD) may conjure up the image of a restless, unfocused school boy. But the disease affects girls as well, and a recent study indicates that when it does, the disorder may persist and be associated with a variety of behavioral and mental health consequences. During adolescence, girls in whom ADHD was diagnosed in childhood were more likely to show symptoms of eating disorders, depression, and substance use disorders than a matched… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2006 at 3:00am — No Comments

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