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PsychiatryRounds Psychiatry News's Blog – March 2007 Archive (40)

Antidepressants Equal to Placebo in Bipolar Depression

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to interested patients that there is controversy over the safety and efficacy of antidepressants for depressed patients with bipolar disorder.



o Explain that this study suggests that antidepressants are safe -- in that they do not cause incidents of mania -- but are not particularly effective in relieving depression in these patients.



o Point out however that the possibility of selection bias in the… Continue

Added by psychiatryRounds Psychiatry News on March 29, 2007 at 10:30pm — No Comments

Antidepressants Equal to Placebo in Bipolar Depression

(PSYCHIATRIC TIMES) - BOSTON, March 29 -- If a depressed patient with bipolar disorder is taking a mood stabilizer such as lithium, adding an antidepressant has no more effect than a placebo, according to researchers here.



In a study of 366 depressed bipolar patients, durable recoveries were nearly identical, whether patients were randomized to an antidepressant or placebo, found Gary Sachs, M.D., of Massachusetts General Hospital here, and colleagues.



Also, there were no… Continue

Added by psychiatryRounds Psychiatry News on March 29, 2007 at 4:00am — No Comments

Binge Eating Disorder: Surprisingly Common, Seriously Under-treated

(PSYCHIATRIC TIMES) - Though binge eating is not an officially recognized disorder, it is more common than anorexia nervosa and bulimia; carries serious health risks; can be chronic; transcends racial, gender and socioeconomic boundaries; and frequently occurs along with other mental disorders.



Given these findings -- taken from the first nationally representative survey of eating disorders in the U.S. -- experts say primary-care physicians should routinely screen for binge eating… Continue

Added by psychiatryRounds Psychiatry News on March 29, 2007 at 4:00am — No Comments

Depression Severity Similar Among Primary Care and Psychiatric Clinics

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Point out to interested patients that patients in primary care setting who have symptoms of major depressive disorder may need further evaluation and, if appropriate, aggressive treatment.



CHAPEL HILL, N.C., March 27 -- Major depression severity is much the same in a psychiatric clinic as it is in the practice of a generalist, reported investigators.



"Conventional wisdom has held that depressed patients in… Continue

Added by psychiatryRounds Psychiatry News on March 27, 2007 at 10:30pm — No Comments

ACC: Depression Shortens Survival in Heart Failure

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to patients that depression is a common comorbidity among heart failure patients and this large record review suggests a need to alert them to need to seek treatment.



o This study was published as an abstract and presented orally at a conference. These data and conclusions should be considered to be preliminary as they have not yet been reviewed and published in a peer-reviewed publication.



NEW ORLEANS,… Continue

Added by psychiatryRounds Psychiatry News on March 25, 2007 at 10:30pm — No Comments

ACC: Depression Shortens Survival in Heart Failure

(PSYCHIATRIC TIMES) - NEW ORLEANS, March 25 -- Heart failure patients who develop clinical depression have a significantly worse survival than those who are not depressed, according to a large Italian record review.



The retrospective review of records of 18,623 heart failure patients found that the 12.3% also diagnosed with depression had an adjusted annual risk of death that was 28% higher than for those not depressed (HR=1.28, 95% confidence interval 1.12-1.47, P<0.0001),… Continue

Added by psychiatryRounds Psychiatry News on March 25, 2007 at 10:30pm — No Comments

Telephone-Based Psychotherapy Shows Durability in Depression

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to interested patients that for depressed patients taking antidepressants, cognitive behavioral psychotherapy delivered in-person or via the phone may bring about long-term improvement.



SEATTLE, March 22 -- For depressed patients on medication but too sad to seek psychotherapy as well, lasting help may be available by phone researchers found in a follow-up study.



For more than 75% of nearly 400… Continue

Added by psychiatryRounds Psychiatry News on March 22, 2007 at 10:00pm — No Comments

Telephone-Based Psychotherapy Shows Durability in Depression

(PSYCHIATRIC TIMES) - SEATTLE, March 22 -- For depressed patients on medication but too sad to seek psychotherapy as well, lasting help may be available by phone researchers found in a follow-up study.



For more than 75% of nearly 400 patients, the positive effects of six months of brief telephone psychotherapy at the start of antidepressant medication endured for 18 months after the first session, including six months beyond the end of all phone therapy, said Evette Ludman, Ph.D., of… Continue

Added by psychiatryRounds Psychiatry News on March 22, 2007 at 9:30pm — No Comments

Alzheimer's Prevalence Tops Five Million in U.S.

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to patients who ask that the increase in Alzheimer's disease prevalence outlined in this report was predicted to occur by epidemiologists and demographic experts, on the basis of the rising occurrence of the disease with age and the "graying" of the U.S. population.



o Note that the prevalence estimates come from an extrapolation of 2003 data.



CHICAGO, March 20 -- More than five million older Americans… Continue

Added by psychiatryRounds Psychiatry News on March 20, 2007 at 10:30pm — No Comments

Alzheimer's Prevalence Tops Five Million in U.S.

(PSYCHIATRIC TIMES) - CHICAGO, March 20 -- More than five million older Americans are living with Alzheimer's disease or other dementias, a 10% increase in prevalence from just five years ago, according to an estimate commissioned by the Alzheimer's Association.

For full article, please visit:
http://www.psychiatrictimes.com/alzheimer-dementia/article/10162/23814

Added by psychiatryRounds Psychiatry News on March 20, 2007 at 10:30pm — No Comments

Anxiety Prevalence High in Primary Care

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to patients who ask that this study found that about one-fifth of patients in 15 primary-care practices surveyed had one of the four most common forms of anxiety disorder, but only about 60% of those with an apparent anxiety disorder were being treated for it.



o Explain that the study was funded by a drug company that makes an antidepressant that is also marketed for treatment of anxiety.



INDIANAPOLIS,… Continue

Added by psychiatryRounds Psychiatry News on March 13, 2007 at 5:30am — No Comments

Anxiety Prevalence High in Primary Care

(PSYCHIATRIC TIMES) - INDIANAPOLIS, March 13 -- Anxiety disorders are as prevalent as depression among patients in primary-care practices, but often go untreated, investigators here have found.



Nearly one in five patients in 15 primary-care practices had signs of anxiety, as determined by a self-administered seven-item questionnaire, but only 61% of those with a possible anxiety disorder were being treated for it, reported Kurt Kroenke, M.D., of Indiana University and the Regenstrief… Continue

Added by psychiatryRounds Psychiatry News on March 13, 2007 at 5:30am — No Comments

Rheumatic Disease Disfigurement Linked to Depression

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Be aware that patients with physical disfigurement from rheumatic disease may be at increased risk for depression.



o This study suggests that patients with rheumatic arthritis and systemic lupus erythematosus should be screened for concerns about body image, even in the absence of objective physical disfigurement.



SYDNEY, Australia, March 12 -- Unhappiness with the appearance of swollen and twisted joints in… Continue

Added by psychiatryRounds Psychiatry News on March 12, 2007 at 11:00pm — No Comments

Rheumatic Disease Disfigurement Linked to Depression

(PSYCHIATRIC TIMES) - SYDNEY, Australia, March 12 -- Unhappiness with the appearance of swollen and twisted joints in the hands and feet of rheumatoid arthritis patients can predict depression, researchers here said.



The same holds true for the skin rashes and lesions characteristic of systemic lupus erythematosus, said Louise Sharpe, M.D., of the University of Sydney here.



Nearly one-third of RA patients reported concerns about their physical appearance, as did more than… Continue

Added by psychiatryRounds Psychiatry News on March 12, 2007 at 11:00pm — No Comments

Imaging Exposes Alzheimer's-Like Plaque in the Human Brain

(PSYCHIATRIC TIMES) - BOSTON, March 12 -- Beta-amyloid plaques in the brains of people with Alzheimer's type dementia can be spotted with the aid of the imaging agent Pittsburgh Compound B, researchers here determined.



The distribution of amyloid plaques seen on positron emission tomography imaging with the tracer compound closely correlated with that discovered post-mortem in a 76-year-old man with Lewy body dementia, reported Brian J. Bacskai, Ph.D., of Massachusetts General… Continue

Added by psychiatryRounds Psychiatry News on March 12, 2007 at 10:30pm — No Comments

Dementia drugs give impetus to early and accurate diagnosis

(PSYCHIATRIC TIMES) - Dementia affects between 1% and 6% of people over the age of 65, and 10% to 20% of those over 80. So as more and more individuals survive into old age, the absolute number of dementia sufferers is likely to soar in the years ahead.



The pharmaceutical industry has been quick to spot this expanding market, and treatments promising to slow the effects of dementia are becoming available. But given the symptomatic similarity of many disorders affecting brain… Continue

Added by psychiatryRounds Psychiatry News on March 9, 2007 at 10:30pm — No Comments

Depression May Affect Blacks More Severely Than Whites

(PSYCHIATRIC TIMES) - BOSTON, March 6 -- Depression tends to be more severe and persistent in blacks than in whites, according to a national epidemiologic study.



Furthermore, less than half of African Americans with depression receive any form of treatment, reported David R. Williams, Ph.D., of the Harvard School of Public Health here, in the March issue of Archives of General Psychiatry.



However, the lifetime prevalence of depression is higher among whites than blacks,… Continue

Added by psychiatryRounds Psychiatry News on March 6, 2007 at 11:00pm — No Comments

Traumatic Stress Induces Brain Change in Children

(PSYCHIATRIC TIMES) - MedPage Today Action Points



o Explain to interested patients that post-traumatic stress disorder (PTSD) is a response to extreme stress that causes a range of long-lasting symptoms.



o Point out that in adults PTSD has been associated with changes in the hippocampus, and in animals it has been shown that the stress hormone cortisol is neurotoxic to hippocampal cells.



o Explain that this study suggests that PTSD is also associated with… Continue

Added by psychiatryRounds Psychiatry News on March 5, 2007 at 9:30pm — No Comments

Traumatic Stress Induces Brain Change in Children

(PSYCHIATRIC TIMES) - STANFORD, Calif., March 5 -- Children with post-traumatic stress disorder, similar to adults, show physical changes in the brain, according to researchers here.



In a pilot study of 15 children, higher PTSD scores and higher cortisol levels were significantly (P<0.05) correlated with relative decreases over time in the volume of the right hippocampus, reported Victor Carrion, M.D., of Stanford, and colleagues, reported in the March issue of… Continue

Added by psychiatryRounds Psychiatry News on March 5, 2007 at 9:00pm — No Comments

What is the best approach for management of depression in a pregnant woman after a suicide attempt?

(PSYCHIATRIC TIMES) - Although suicidal ideation occurs in roughly 5% to 14% of pregnancies,1 suicide attempts are relatively rare (0.04%) and are associated with substance abuse and poor pregnancy outcome.2 After a suicide attempt, the clinician must first consider the possibility of recurrence of self-destructive behavior by assessing the woman's motivation, her attitude toward the pregnancy, and the severity of her depressive symptoms.



The quality of a pregnant woman's social… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2007 at 11:00pm — No Comments

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