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September 2009 News and Blog Posts (10)

Atypical Antipsychotics for Treating Major Depression

(PSYCHIATRIC TIMES) - Major depressive disorder (MDD) does not always respond to antidepressants. Whether we are using SSRIs, serotonin-norepinephrine reuptake inhibitors (SNRIs), tricyclics, monoamine oxidase inhibitors, or heterocyclics (trazodone, nefazodone, bupropion), the result often falls short of full remission of symptoms. In the large National Institute of Mental Health Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial, only about 30% of patients achieved… Continue

Added by psychiatryRounds Psychiatry News on September 19, 2009 at 10:00pm — No Comments

On integrity and never ending diagnostic updates…

(PSYCHIATRIC TIMES) - I read the article by Dr Frances and was impressed by its intelligence. I then read the response by the APA in the person of Dr Schatzberg et al. I was shocked by its sleazy attack on Dr Frances’ integrity. Dr Frances was accused of arguing because of anticipated personal financial gain. The accusation that Dr Frances was arguing ad hominem was the pot calling the kettle black.



For full article, please visit:…

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Added by psychiatryRounds Psychiatry News on September 17, 2009 at 5:00am — No Comments

Toward mental illness for all?

(PSYCHIATRIC TIMES) - We were surprised to read of the open letter by Drs Frances and Spitzer regarding the creation of DSM-V. Over time we have been puzzled by a succession of Diagnostic and Statistical Manuals, and have been forced to conclude the long-term purpose of the DSM is to abolish mental illness from American society. Currently only half of all Americans fit the criteria in DSM-IV to be diagnosed with one kind of mental illness or another. 1 Surely the goal of DSM-V must be to… Continue

Added by psychiatryRounds Psychiatry News on September 16, 2009 at 5:00am — No Comments

Study Shows Migraineurs With Comorbid Mood Disorders Responded Well to Treatment

(PSYCHIATRIC TIMES) - Patients with migraine accompanied by depression or anxiety disorders had greater improvements in headache-related disability than those without a psychiatric disorder, according to results of the Treatment of Severe Migraine trial.1 Before this study, it was commonly assumed that patients with migraine and a psychiatric comorbidity do not fare as well during treatment, said Elizabeth Seng, MS, a graduate student at Ohio University in Athens, who presented the results at… Continue

Added by psychiatryRounds Psychiatry News on September 14, 2009 at 8:00pm — No Comments

Lamotrigine in Acute Bipolar Depression: Two Thumbs Up—or One?

(PSYCHIATRIC TIMES) - I just read and enjoyed “Treatment-Resistant Bipolar Disorder”1 at www.PsychiatricTimes.com, and wanted to thank the author for pulling together a great deal of useful information in a succinct and lucid format.



There are, of course, many areas of controversy in the literature, and one of those concerns the utility of lamotrigine in acute bipolar depression. Would Dr Chou comment on the “++” rating for lamotrigine in… Continue

Added by psychiatryRounds Psychiatry News on September 9, 2009 at 9:00pm — No Comments

ADHD & ODD: Confronting the Challenges of Disruptive Behavior

(PSYCHIATRIC TIMES)- ABSTRACT: Disruptive behavior is the most common mental health problem seen by pediatricians. Although attention-deficit/ hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD) are both considered disruptive behavior disorders—and although about half of children with ADHD also meet the diagnostic criteria for ODD—the 2 disorders are distinct, having different etiologies and responding to different types of treatment. ADHD is generally viewed as a… Continue

Added by psychiatryRounds Psychiatry News on September 9, 2009 at 7:30am — No Comments

Lamotrigine in Acute Bipolar Depression: Two Thumbs Up—or One?

(PSYCHIATRIC TIMES) - I just read and enjoyed “Treatment-Resistant Bipolar Disorder”1 at www.PsychiatricTimes.com, and wanted to thank the author for pulling together a great deal of useful information in a succinct and lucid format.



There are, of course, many areas of controversy in the literature, and one of those concerns the utility of lamotrigine in acute bipolar depression. Would Dr Chou comment on the “++” rating for lamotrigine in… Continue

Added by psychiatryRounds Psychiatry News on September 9, 2009 at 3:00am — No Comments

Electroconvulsive Therapy: A Guide for Professionals and Their Patients

(PSYCHIATRIC TIMES) - This book is well-written and concise. It provides an overview of ECT that is evidence-based yet understandable by the average person. The author effectively uses clinical anecdotes to provide a “face” for the science. The book is organized in a user-friendly way.



Patients are most likely to be interested in the first 6 chapters. The remaining chapters complete an overview of ECT that will be more relevant to clinicians.



A brief introductory chapter… Continue

Added by psychiatryRounds Psychiatry News on September 4, 2009 at 5:30am — No Comments

This Accusation Has No Logic. . .

(PSYCHIATRIC TIMES) - The APA DSM-V Task Force’s response to Dr. Frances’s critique of DSM-V noted that his royalties for DSM-IV products would cease when DSM-V is published. However, Dr. Frances’ critique called for DSM-V developers to make fewer changes- - not more, and he made no call for longer DSM-V field trials; in fact he proposed additions such as prodromal and subthreshold syndromes to be put in an appendix that called for further research. His critique then would not extend his… Continue

Added by psychiatryRounds Psychiatry News on September 3, 2009 at 5:00am — No Comments

MRI software predicts Alzheimer's disease

(PSYCHIATRIC TIMES) - Massachusetts General Hospital researchers are using automated MRI software to detect individuals in the preclinical phase of Alzheimer's disease with 95% accuracy.



Dr. Rahul Desikan, a researcher at MGH, and colleagues identified which regions of the brain are affected by AD and mild cognitive impairment in two patient groups of 97 and 216, respectively. Based on earlier pathological and imaging studies, the investigators confirmed that those with AD or MCI… Continue

Added by psychiatryRounds Psychiatry News on September 1, 2009 at 3:00am — No Comments

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