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April 2008 News and Blog Posts (13)

Pittsburgh Compound B offers early proof of Alzheimer’s

(PSYCHIATRIC TIMES) - Though University of Pittsburgh Alzheimer's disease researchers believed it all along, groundbreaking research now confirms that Pittsburgh Compound B binds to the beta-amyloid deposits found in the brains of patients with Alzheimer's. The finding is a major step toward an early, definitive diagnosis of the memory-stealing disease in living patients.



"As excited as researchers get, we are pretty excited," said senior author Dr. Steven T. DeKosky, a professor of… Continue

Added by psychiatryRounds Psychiatry News on April 23, 2008 at 9:00pm — No Comments

Common Issues in Female Sexual Dysfunction

(PSYCHIATRIC TIMES) - "I've lost my interest in sex." As psychiatrists, we hear this concern (if we ask) from women in a variety of situations: those who are depressed, postpartum, menopausal, traumatized, and those who have been treated with psychotropic medications. Thankfully, we have many interventions, both behavioral and pharmacological, to use in addressing sexual issues.



Patients are often reticent about bringing up sexual problems or asking for solutions to sexual issues and… Continue

Added by psychiatryRounds Psychiatry News on April 15, 2008 at 11:30pm — No Comments

Can Atypical Antipsychotics Reduce Suicide Risk in Patients With Schizophrenia?

(PSYCHIATRIC TIMES) - Suicide is a devastating, tragically frequent outcome for persons with varying psychiatric conditions, including schizophrenia. An estimated 5% to 10% of persons with schizophrenia commit suicide and 20% to 50% attempt suicide during their lifetime.1,2 Patients with schizophrenia have more than an 8-fold increased risk of completing suicide (based on the standardized mortality ratio) than the general population.3 Antipsychotic treatment is the cornerstone of the… Continue

Added by psychiatryRounds Psychiatry News on April 15, 2008 at 10:30pm — No Comments

The Muscarinic Hypothesis of Schizophrenia Implications for Pharmacological Treatment

(PSYCHIATRIC TIMES) - Since the discovery of dopamine as a neurotransmitter in the late 1950s, schizophrenia has been associated with changes in the dopaminergic system. However, the dopamine hypothesis of schizophrenia cannot explain all the symptoms associated with this disorder. Therefore, research has also focused on the role of other neurotransmitter systems, including glutamate, g-aminobutyric acid, serotonin, and acetylcholine (ACh) in schizophrenia.



Recently, schizophrenia… Continue

Added by psychiatryRounds Psychiatry News on April 15, 2008 at 10:30pm — No Comments

Cultural Aspects of the Pharmacological Treatment of Depression: Factors Affecting Minority and Youth

(PSYCHIATRIC TIMES) - The cultural and demographic profile of the United States is undergoing a rapid transformation. In many areas of the country, there is no longer an ethnic majority but a multiplicity of racial and cultural groups. These changes can be attributed to 3 principal factors1:



• The aging and lower fertility rates of the European origin population.

• The significant increase of immigration from developing countries, especially from Latin American and Asia.

•… Continue

Added by psychiatryRounds Psychiatry News on April 15, 2008 at 10:00pm — No Comments

The Complex Interrelationships of Menstrual Cyclicity and Anxiety Disorders

(PSYCHIATRIC TIMES) - The ocurrence and severity of anxiety disorders have been correlated with fluctuations in female sex steroid levels in both epidemiological and experimental studies.1-5 Female reproductive hormones play a role not only in the development and course of anxiety disorders but also in treatment response.1,2,6-12 This article focuses on the premenstrual exacerbation of anxiety disorders and briefly reviews the biological pathways and physiological mechanisms thought to… Continue

Added by psychiatryRounds Psychiatry News on April 15, 2008 at 5:00am — No Comments

Focus on Bipolar Disorder

(PSYCHIATRIC TIMES) - Although several antimanic agents are available to treat individuals with bipolar disorder (BD), many patients have a less than satisfactory response or experience adverse effects.1 With the exception of lithium, all of the current antimanic agents are either anticonvulsant or antipsychotic drugs. It is remarkable that no drug has been developed specifically for BD, especially because this illness was conceptualized more than a century ago. The lack of available… Continue

Added by psychiatryRounds Psychiatry News on April 15, 2008 at 3:30am — No Comments

Focus on Bipolar Disorder

(PSYCHIATRIC TIMES) - Although several antimanic agents are available to treat individuals with bipolar disorder (BD), many patients have a less than satisfactory response or experience adverse effects.1 With the exception of lithium, all of the current antimanic agents are either anticonvulsant or antipsychotic drugs. It is remarkable that no drug has been developed specifically for BD, especially because this illness was conceptualized more than a century ago. The lack of available… Continue

Added by psychiatryRounds Psychiatry News on April 15, 2008 at 3:30am — No Comments

Rates of Depressive Episodes, Psychological Distress Decline

(PSYCHIATRIC TIMES) - The highest rate of nonspecific serious psychological distress (SPD) (14.4%) among persons aged 18 and older in 2005 and 2006 was found in Utah, but overall, national SPD rates declined slightly. The rates of major depressive episodes (MDEs) among youths aged 12 to 17 years in Utah decreased significantly, from 10.1% in 2004 to 2005 to 8.2% from 2005 to 2006, according to a report released on March 6 by the Substance Abuse and Mental Health Services Administration… Continue

Added by psychiatryRounds Psychiatry News on April 1, 2008 at 10:30pm — No Comments

Does Infection Increase Risk of Psychosis and Schizophrenia?

(PSYCHIATRIC TIMES) - New research is examining the link between schizophrenia/psychosis and select infections affecting the CNS. Two reports investigated this link in children and military personnel in the January 2008 issue of the American Journal of Psychiatry.



A study conducted by Dr Christina Dalman and associates found that serious infections in the CNS during childhood may play a role in the later development of schizophrenia and nonaffective psychoses, although only to a… Continue

Added by psychiatryRounds Psychiatry News on April 1, 2008 at 10:30pm — No Comments

Task Force Proposes New Bipolar Guidelines

(PSYCHIATRIC TIMES) - An international team of experts recently proposed expanding the diagnostic criteria for several subtypes of bipolar disorder, adding a pediatric bipolar disorder category and eliminating the schizoaffective disorder category.



The Diagnostic Guidelines Task Force of the International Society for Bipolar Disorder (ISBD) has been examining diagnostic issues since 2004 and recently presented its recommendations at ISBD's third biennial meeting in India and in the… Continue

Added by psychiatryRounds Psychiatry News on April 1, 2008 at 3:30am — No Comments

Integrative Treatment for Adult ADHD: A Practical, Easy-to-Use Guide for Clinicians

(PSYCHIATRIC TIMES) - Although there is evidence in the research literature from as far back as 40 years showing that the symptoms of attention-deficit/hyperactivity disorder (ADHD) often persist into adulthood, it has been only in the past decade or so that integrative treatment models designed specifically for adult ADHD have been developed. While there has not been a systematic empirical study of integrative, multimodal treatments for adult ADHD, there is a growing clinical research… Continue

Added by psychiatryRounds Psychiatry News on April 1, 2008 at 2:00am — No Comments

Sleep Disorders in the Elderly

(PSYCHIATRIC TIMES) - Psychiatric Times - Category 1 Credit

o earn AMA PRA Category 1 Credit(s)™:

Read the article "Sleep Disorders in the Elderly" from the April 2008 issue of Psychiatric Times, complete the posttest and the evaluation. (Note: A score of at least 70% must be achieved in order to be awarded credit.)



The posttest will be scored instantly and results will be shown onscreen. Please make a copy of your test results for your continuing education records. After… Continue

Added by psychiatryRounds Psychiatry News on April 1, 2008 at 1:00am — No Comments

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