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March 2008 News and Blog Posts (14)

Clinical FDG-PET use grows as research moves forward

(PSYCHIATRIC TIMES) - Molecular imaging has been redefined. By expanding its definition to apply to most diagnostic and therapeutic procedures formerly associated with nuclear medicine, diagnostic imaging’s leaders hope to make molecular imaging relevant and accessible to mainstream radiology.



MI’s journey from bench to bedside is not going to be easy. Researchers need more time to guide promising applications from preclinical animal testing into practice. Yet progress can be seen on… Continue

Added by psychiatryRounds Psychiatry News on March 4, 2008 at 9:00pm — No Comments

Considering Genetics in Sexual Offenders

(PSYCHIATRIC TIMES) - When I finished reading "Sexual Offenders With Mental Issues: Special Considerations for a Special Population," (Psychiatric Times, September 2007) I could hardly believe that Dr Rotter had not mentioned genetics! This is infinitely more important than whether sexual offenders are mentally ill! A genetic basis tells us "what to do about individuals who have been convicted of sexual crimes," and unequivocally supports that "over the past decade, we have witnessed… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 11:30pm — No Comments

Issues in Family Services for Persons With Schizophrenia

(PSYCHIATRIC TIMES) - Extensive evidence supports the importance of the involvement of families in the mental health care of patients with schizophrenia and other serious mental illnesses. Family involvement is endorsed by the President's New Freedom Commission1 and the American Psychiatric Association Practice Guidelines on schizophrenia.2 Up to 75% of people with schizophrenia are in regular contact with their families,3 and more than one third of individuals with schizophrenia live with… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 10:30pm — No Comments

Schizophrenia: Some Neglected Topics

(PSYCHIATRIC TIMES) - It is a pleasure to introduce this series of 4 special articles on schizophrenia. As industry support has shaped postgraduate psychiatric education, the quantity of educational programs has grown dramatically while the breadth of topics has not. Within the field of schizophrenia, subjects related to the prescribing of newer antipsychotic agents are covered extensively, often with particular emphasis on the critical topic of metabolic complications.



Within these… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 10:30pm — No Comments

Negative Symptoms in Schizophrenia: The Importance of Identification and Treatment

(PSYCHIATRIC TIMES) - Schizophrenia is among the top 10 disabling conditions worldwide for young adults.1,2 In the United States, the cost of treatment and loss in productivity associated with schizophrenia are estimated to be as high as $60 billion annually.3-5 More than three quarters of this amount is associated with loss in productivity.1 Patients with schizophrenia struggle with many functional impairments, including performance of independent living skills, social functioning, and… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 10:30pm — No Comments

Atypical Antipsychotics for Treatment of Schizophrenia Spectrum Disorders

(PSYCHIATRIC TIMES) - The number of prescriptions for antipsychotic treatment of teenagers has increased sharply in office-based medical practice.1 Adolescents with psychotic symptoms frequently present for clinical evaluation, and early-onset schizophrenia spectrum disorders (onset of psychotic symptoms before the age of 18 years) represent an important consideration in the differential diagnosis in these youths. The onset of schizophrenia occurs by the age of 19 in nearly 40% of male patients… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 10:30pm — No Comments

Nicotine Dependence in Schizophrenia: Prevalence, Mechanisms, and Implications for Treatment

(PSYCHIATRIC TIMES) - Each year more than 440,000 people in the United States die of smoking-related illness, and nearly half a billion dollars in health-related economic losses are directly attributable to smoking.1,2 Cigarette smoking has been the single largest source of preventable morbidity and mortality in the United States for the past 29 years, and the global mortality toll of smoking, 5 million annually, is on the rise.3 Smokers die on average 10 years earlier than lifelong nonsmokers,… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 10:30pm — No Comments

Common Augmentation Strategies for Depression: Findings Show Lack of Evidence

(PSYCHIATRIC TIMES) - It is estimated that at least half of persons who begin antidepressant treatment will not respond to monotherapy.1 When a single antidepressant is ineffective, the addition of 1 or more medications to enhance mood and overall antidepressant response is common.2 While it is hoped that such augmentation strategies will be effective, drug augmentation has drawbacks, including increased cost, unclear dosing strategies, and the possibility of drug-drug interactions.3 A review… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 10:00pm — No Comments

Buddhists Meet Mind Scientists in Conference on Meditation and Depression

(PSYCHIATRIC TIMES) - On October 20, 2007, leading researchers in the fields of mood disorders and meditation discussed the promise—and limitations—of meditation for the prevention and treatment of major depression. Participating in a day-long symposium titled "Mindfulness, Compassion, and the Treatment of Depression" was His Holiness the Dalai Lama. The event, which drew an audience of more than 3000, was cosponsored by Emory University in Atlanta and the Mind & Life Institute and was the… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 10:00pm — No Comments

Of Estrogen, Alzheimer's, and Male and Female Brains

(PSYCHIATRIC TIMES) - I have read both that the male brain has no estrogen receptors and that testosterone is converted to estrogen in the brain. Where does the truth lie? And what role, if any, does estrogen play in preventing Alzheimer disease in both men and women?



-----Malcolm Wagner, MD

Porterville, Calif











The male brain does have estrogen receptors. The profound effects of estrogen on different tissues, including the brain—in both men and… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 9:00pm — No Comments

Overcoming Resistant Personality Disorders: A Personalized Psychotherapy Approach

(PSYCHIATRIC TIMES) - Theodore Millon and Seth Grossman;

New York: John Wiley & Sons, 2007

344 pages • $49.95 (softcover)



Overcoming Resistant Personality Disorders is a provocative and well-reasoned, yet frustrating volume. In it, the authors challenge various authorities on the subject; for example, they criticize the DSM for its failure to "officially endorse an underlying set of principles that would interrelate and differentiate the categories in terms of their… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 9:00pm — No Comments

Effective Pharmacological Treatment Options for Anxiety Disorders

Cumulative research with animal, normative, and clinical populations over several decades shows that the mechanisms underlying anxiety disorders differ from those of the normal emotion of anxiety. In persons with anxiety disorders, fear and tension are disproportionate to the actual threat and may be present when no real threat exists, thereby generating an expectation of danger and distorted perceptions related to danger and various types of threats. The most common anxiety disorders are… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 5:00am — No Comments

The Neurochemistry of Pediatric Major Depressive Disorder

(PSYCHIATRIC TIMES) - Major depressive disorder (MDD) in pediatric populations represents a significant public health concern. Rates of MDD rise dramatically in adolescence, with an estimated lifetime prevalence of 15% in adolescents aged 15 to 18.1 MDD is associated with severe consequences, including deterioration in academic functioning, increased risk of substance use and other mental disorders, and most critically, attempted and completed suicides—the third leading cause of death in this… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 3:30am — No Comments

Posttraumatic Stress Disorder: Neurobiology, Psychology, and Public Health

(PSYCHIATRIC TIMES) - In recent years, we have learned a great deal about posttraumatic stress disorder (PTSD) and its public health implications. From 9/11 to Katrina and the present Iraq war, PTSD has been in the forefront of health concerns and public policy. Recent advances as well as emerging needs are leading us to new and exciting opportunities to provide better care and gain a better understanding of the complex nature of human responses to traumatic events. As we look to the future, we… Continue

Added by psychiatryRounds Psychiatry News on March 1, 2008 at 3:30am — No Comments

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