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February 2008 News and Blog Posts (9)

Antidepressant Study Revives Efforts to Establish Public Clinical Trial Registry

(PSYCHIATRIC TIMES) - The American Psychiatric Association (APA) and the American Academy of Child and Adolescent Psychiatry (AACAP) renewed their 2004 call for a mandatory public clinical trial registry to be established and overseen by the federal government. This is in response to a study that showed that research on antidepressants is published selectively—effectively suppressing trials deemed negative and overstating the benefits of antidepressant therapy. The study was published in the… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 10:30pm — No Comments

Panic-Focused Psychodynamic Psychotherapy

(PSYCHIATRIC TIMES) - Both cognitive-behavioral1-3 and pharmacological4-6 treatments for panic disorder have been found to be effective over the short term. Not all patients, however, can tolerate or fully respond to these approaches,1-3,7,8 and the effectiveness of these interventions over the long term remains unclear.1,9 The degree to which these treatments affect psychosocial and quality-of-life impairments associated with panic disorder is uncertain because of limited data.10,11 Given the… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 9:30pm — No Comments

Agitation in Dementia: Update and Prospectus

(PSYCHIATRIC TIMES) - Two years ago, probable Alzheimer disease (AD) was diagnosed in the mother to whom this message refers. Her family has made a brave effort, despite her declining comprehension and diminishing ability to care for herself, to honor an earnest plea she made at that time. Increasingly aware of her cognitive difficulty, she asked her family to do everything possible to avoid ever sending her to a nursing home, a setting associated in her mind with very unpleasant memories of… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 9:00pm — No Comments

Second Messenger Systems, Genes, Neurogenesis, and Mood Disorders

(PSYCHIATRIC TIMES) - Most important, antidepressants do not work as quickly or as effectively as the original monoamine hypothesis would suggest. Monoamine action also does not explain much of the clinical activity of diverse mood stabilizers (lithium [Eskalith, Lithobid], valproic acid [Depakote, Depakene], carbamazepine [Carbatrol, Tegretol]), and some atypical antipsychotics. In addition, the monoamine theory fails to account for recent evidence concerning structural changes within the… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 8:00pm — No Comments

Treatment Planning for Panic Disorder

(PSYCHIATRIC TIMES) - Panic disorder with or without agoraphobia is a chronic, debilitating psychiatric illness that affects about 4.7% of the general US population.1 Kessler and colleagues2 report that close to one third of the general population has met criteria for panic disorder within the past year.2 The mean age at onset is in one's 20s, and women are twice as likely as men to present with panic disorder.3



Panic disorder is associated with poor quality of life4,5 and with… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 5:30am — No Comments

Anxiety Disorders

(PSYCHIATRIC TIMES) - Anxiety disorders are some of the most common mental health problems that confront clinicians, either as a primary diagnosis or as comorbid conditions.1 In addition to the cost to the individuals who have these medical illnesses, there is an enormous cost to society when these illnesses are not effectively treated.2 There continues to be a great need for developing new treatments and improving those we already have.



The mental health morbidity that is… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 5:00am — No Comments

Developing an Effective Treatment Protocol

(PSYCHIATRIC TIMES) - Anxiety disorders are the most prevalent disorders among children and adolescents in both community and clinical settings. The high prevalence of anxiety disorders in children and adolescents leads to increased interest in the development and implementation of effective treatments. Anxiety disorders in children and adolescents are often associated with significant psychosocial impairments (eg, poor social relationships, decrease in academic performance, low self-esteem),… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 5:00am — No Comments

Posttraumatic Stress Disorder in Veterans

(PSYCHIATRIC TIMES) - There have been nearly 1.5 million military deployments to the southwest Asian combat zone since the start of the Afghanistan operation and Iraq war in 2001 and 2003, respectively. There have been many casualties, some of which have been highly profiled, such as service members being killed in action, losing limbs, or suffering blast injuries to their brain. Although these casualties are tragic and life-altering—both for the soldiers and their families—they represent a… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 3:30am — No Comments

Brain Maturation Delayed, Not Deviant, in Kids With ADHD

(PSYCHIATRIC TIMES) - Cortical development in children with attention-deficit/hyperactivity disorder (ADHD) generally lags behind that in other children by several years, NIMH researchers reported recently.1 The greatest maturational delay occurs in prefrontal regions important for control of such cognitive processes as attention and working memory, they found.



There has been a long-standing debate as to whether ADHD is caused by a delay in brain development or is partly due to a… Continue

Added by psychiatryRounds Psychiatry News on February 1, 2008 at 2:30am — No Comments

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